By now everyone has heard of CBD. From Martha Stewart’s french bulldog taking CBD for anxiety to Kim Kardashian using it to fall asleep, CBD is now becoming ubiquitous with relaxation and health. In just 2 years of legalization, the CBD industry has generated $4.6 billion in sales. But now CBDA, a new kid on the block, is starting to rise in popularity. 

What is CBDa vs. CBD?

Both CBDa & CBD molecules are cannabinoids that come from the Cannabis plant. The cannabis plant contains at least 113 cannabinoids. However, the exact concentration will depend on the type of plant.

CBDa (cannabidiolic acid)  is the pre-cursor to CBD. In other words, CBDA is the raw, natural form of CBD! Given time, this natural form will eventually convert to CBD by releasing its acid molecule. Decarboxylation occurs when heat is added.

CBDa did not garner the initial interest because of the precedence set by THC, the main psychoactive compound in cannabis that produces a high sensation. It was widely known that the benefits of THC can only be retrieved when the flower is heated. The same assumption was made with CBDa, thereby, there were more studies made on CBD. 

CBDa doesn’t bind to cannabinoid receptors the way that CBD does. But it does interact with the body’s endocannabinoid system and boosts serotonin production. 

Image: Kalapa-Clinic

What Does CBDa Do?

As more studies are being conducted, the overlooked molecule is starting to show higher effectivity against inflammation compared to CBD.  CBDa selectively inhibited cyclooxygenase (COX)-2 activity by 50% inhibition concentration.

COX-2 inhibitors are a type of nonsteroidal anti-inflammatory drug (NSAID) that directly targets cyclooxygenase-2, COX-2, an enzyme responsible for inflammation and pain. Targeting selectivity for COX-2 reduces the risk of peptic ulceration.

CBDa is also is absorbed better by the body, increasing its bioavailability so the dosage can start at a lower level.  It also has shown to be supportive in preventing cancer as well as supporting cancer therapy by being anti-nausea and anti-vomiting also known as Anti-emetics.

Anti-emetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anesthetics, and chemotherapy directed against cancer.

What is the best way to take CBDa?

We recently interviewed Dr. Tom Piccariello, Chief Scientist of ChyloCure, to discuss the latest advancement in CBDa.

He recommends taking Chylocaps because it takes into account the most up-to-date CBDa delivery technology. Designed for increased bioavailability and greater potency, you can take less and benefit more. The raw hemp extract-rich capsules are easy to swallow and are infused with magnesium to offer effortless, consistent dosing, and are convenient for those on the go.

If you want to learn more about cannabis, mushrooms, and herbal remedies, check out our course on demand.



Ezza Valdez

Ezza Valdez is an explorer with a creative passion for "DIY" projects. Growing up in the Philippines, she rallied her friends to adventures in outdoor cooking (using milk cans as pots), paper doll theatrics, and making their own musical instruments for caroling. "You can make beautiful music with a wire and a ton of bottle caps". A veteran of the IT industry with an academic background in Computer Science and Technology, she is currently a student at David Winston's Herbal Studies 2-year program.

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